Brian Tseng

As a board-certified M.D., Ph.D. pediatric neurologist/neuromuscular physician–scientist, Brian Tseng now serves as the CEO for The POLG Foundation which is on a laser-focused mission set out by our beloved Frederik. Since 2003, Brian has been the Chief Scientific Officer for the Foundation and brings a vast depth of experience in therapeutic development. He has led large cross-functional teams (Novartis, AveXis, Vertex) to develop and bring forward many new medicines approved for use in infants and children with rare genetic disorders. As a retired vice president from top R&D companies, he has deep 20+ years of experience in translational and clinical development of novel molecules (small, biologic, cell-based, AAV genetic replacement, and CRISPR-mediated gene editing). His past clinical/academic practice has been at Massachusetts General Hospital/Harvard Medical School and at Children’s Hospital Colorado. His physiology undergraduate degree is from University of California Berkeley and he has a Ph.D. in molecular biology from MD Anderson Cancer Center/University of Texas at Houston McGovern Medical School. He is also a Parkmedic for Search and Rescue efforts in Rocky Mountain National Park and serves on the Board of the N=1 Collaborative N1C n1collaborative.org for ultrarare disorders.