Our Leadership
Guided by Expertise
Meet the leaders, advisors, and board members driving The POLG Foundation's mission forward.
Board of Directors
Robert de Luxembourg
Co-Founder, Chair
Business leader and CEO in wine and hospitality, actively engaged in cultural and philanthropic initiatives.
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Julie de Luxembourg
Co-Founder, Vice Chair
Mother and advocate dedicated to education, justice, human rights, music, and curing POLG disorders.
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Steven M. Altschuler
M.D. / Director
Biotech leader and healthcare innovator, co-founder of Spark Therapeutics, advancing transformative gene therapies.
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Rémy Best
Director
Managing Partner at Pictet Group, supporting humanitarian, cultural, and educational initiatives worldwide.
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Jörg Duschmalé
Ph.D. / Director
Roche board member and chemist, combining drug discovery expertise with rare disease advocacy.
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Cindy Price Gavin
Director
Nonprofit leader and strategist, building medical start-ups into trusted patient advocacy organizations.
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Allyson J. Ocean
M.D. / Director
Oncologist and professor at Weill Cornell, advancing research, patient advocacy, and innovative cancer therapies.
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Brian Tseng
M.D., Ph.D. / Director
Neurologist and physician–scientist, pioneering therapies for rare genetic disorders in children worldwide.
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Jennifer Adams
M.D. / Director
Physician and educator at NYU, advancing empathy, primary care, and medical education leadership.
Read MoreScientific Advisory Board
Steven M. Altschuler
M.D. / Chairman of the SAB
Biotech leader and healthcare innovator, co-founder of Spark Therapeutics, advancing transformative gene therapies.
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Laurence A. Bindoff
M.D., Ph.D.
Neurologist and researcher specializing in mitochondrial disease, contributing key discoveries and clinical insights for decades.
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Luca Bolliger
Ph.D.
Biochemist and industry leader with 20+ years’ experience in pharma, licensing, and biotech entrepreneurship.
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Jörg Duschmalé
Ph.D.
Roche board member and chemist, combining drug discovery expertise with rare disease advocacy.
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Federico Mingozzi
Ph.D.
Chief Science & Technology Officer at Spark Therapeutics, global leader in gene therapy and immunology.
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Arnold Munnich
M.D., Ph.D.
Pediatrician and geneticist, founder of the Imagine Institute, pioneering advances in childhood genetic disorders.
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Brian Tseng
M.D., Ph.D.
Pediatric neurologist and physician–scientist, advancing novel therapies for rare genetic diseases in children.
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Doug Turnbull
M.D., Ph.D.
Emeritus Professor of Neurology at Newcastle University, renowned expert in mitochondrial disease and aging.
Read MorePOLG Leadership
Brian Tseng
M.D., Ph.D. / Chief Executive Officer
Pediatric neurologist and biotech leader, CEO advancing research and therapies for rare genetic disorders.
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Luca Bolliger
Ph.D. / Chief Scientific Officer
Biochemist and industry leader with 20+ years’ experience in pharma, licensing, and biotech entrepreneurship.
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Paula Casanova
Chief Operating Officer
Global operations leader with experience in startups and nonprofits, driving The POLG Foundation’s mission forward.
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Julie de Luxembourg
Co-Founder, Vice Chair
Advocate for education, justice, and human rights, co-founder dedicated to curing POLG disorders.
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Frederik de Nassau
Co-Founder, Creative Director
POLG patient and creative director, whose resilience inspired the Foundation’s design, voice, and mission.
Read MoreExplore the Science
Learn how our research drives discovery, collaboration, and progress toward a cure.
Join the Mission
Whether through giving or action, your support helps accelerate the path to a cure.
